Drug name: Lisinopril

Active substance: Lisinopril

Pharmacological effects: Lisinopril belongs to a group of medicines called angiotensin converting enzyme inhibitors or ACE inhibitors for short. By interfering with the activity of this enzyme, Lisinopril reduces the production of angiotensin II. Angiotensin II is vasocontrictive agent that narrows blood vessels causing high blood pressure. By acting on ACE lisinopril also lowers the synthesis of aldosterone resulting in decreased diuresis and reduced blood volume.

Indications: Lisinopril is approved for the treating of the following cardiovascular conditions:

• High blood pressure controlling
• Congestive heart failure treatment
• Treatment of cardiovascular diseases in post infarction period

Warnings and Precautions: The drug should not be used in the following conditions:

• Hypersensitivity to any components of the preparations.
• History of angioedema associated with therapy with ACE inhibitors
• Hereditary or idiopathic angioedema.
• Pregnancy
• Lactation(breastfeeding)

Let your doctor know if you experience the following health problems:

• Cardiovascular diseases(aortic stenosis, or hypertrophic cardiomyopathy)
• Liver and kidney diseases
• Diabetes
• Signs of angioedema
• Scleroderma
• Systemic lupus erythematosus
• Diseases of the hematopoietic system
• Stenosis of the renal arteries
• Condition after renal transplantation
• Decreased blood volume

Inform your doctor if you are dialysis or going to have any surgical interventions

Lisinopril side effects: Drugs may cause side effects which in specific patients may manifest differently. In the following paragraph we want to underline the most serious and frequent side effect of Lisinopril that were identified by the drug manufacturers. The possibility of the adverse effect manifestation depends only on the individual and his specific traits.

The most common Lisinopril side effects include:

• Digestive system: stomach pain, diarrhea, vomiting, nausea
• CNS: Headache, dizziness, fatigue, cough
• Cardiovascular system: chest pain, low blood pressure
• Other: erectile dysfunction, infections of the upper airways, skin rash, kidney problems

The less common Lisinopril side effects included:anemia, insomnia, joint pain, pelvic pain, pancreatitis, heartburn, abnormal heart rhythm, infections of the urinary system

For full information on any risks and adverse effects associated with Lisinopril, please consult your doctor, read the included leaflet or contact our customer support service.

Interactions: Before using Lisinopril please tell your doctor which drugs or supplements you are already taking including those bought without a prescription. Also check if any additional medicine which you will take during the course of Lisinopril therapy are safe in combination. Especially mention if you are taking the following groups of drugs:

• Diuretics(water pills). Diuretics enhance the effects of Lisionopril
• NSAID's. Nonsteroidal Anti-Inflammatory Drugs may increase the risk of kidney damage
• Potassium supplements and potassium sparing diuretics. Potassium preparations may cause high potassium blood levels.
• Lithium preparation. Lisinopril may increase the amount of lithium blood levels

Patients information: Lisinipril is not to be shared with healthy individuals. It is strictly FORBIDDEN to use the drugs in treatment of any conditions unrelated to their indications. The product as well as utilized vials, syringes, needles if used during the course of treatment should be kept out of reach of children and never reused.