Drug name: Vardenafil
Other names used:

Therapeutic actions: The active ingredient of Vardenafil tablets is vardenafil. Vardenafil prevents the action of phosphodiesterase which breaks down cyclic GMP in the blood vessel walls. Cyclic GMP relaxes blood muscles and increases blood flow to penis. Penis becomes erect and rigid. Inhibiting the action of phosphodiesterase causes stopping the breakdown of cyclic GMP. Blood vessels can be dilated for longer, increasing blood flow to the penis and maintaining an erection.

Indications: Vardenafil is used to treat:

• erectile dysfunction(Impotence) in men.

Contraindications and cautions:
You should not use Vardenafil:

• if you are allergic to Vardenafil
• in adolescents or children under 18 years of age
• if you are women
• Severely liver insufficiency
• Severely kidney insufficiency
• If you have galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.
• if you have severe heart disorders (unstable angina , heart failure)
• if have recently had a heart attack
• if you have low blood pressure
• if you taking nitrate medications, eg glyceryl trinitrate , antiarrhythmics (eg, quinidine, amiodarone)
• if you have a stroke
• if you have hereditary degeneration of the back of the eyeball (retina), such as retinitis pigmentosa
• if you are taking drugs called "poppers" (eg, amyl nitrate, butyl nitrate)

You should talk with your health care provider prior to taking Vardenafil

• in elderly people
• if you have kidney disorders
• if you have liver disorders
• Diseases of the heart and blood vessels
• if you have aortic stenosis - narrowing of the aorta
• if you experience bleeding disorders, (haemophilia)
• if you have stomach disease such as peptic ulcer
• if you have physical abnormality of the penis, such as severe curvature, scarring or Peyronie's disease
• if you have bone cancer or leukaemia in which there is an increased risk of prolonged erections (priapism)

Warning!

• Vardenafil can cause visual disturbances and dizziness, it is not recommend to operate machinery.
• You should use Vardenafil on an empty stomach.
• You should use Vardenafil with caution with grapefruit juice while it can increase possible side effects.
• Vardenafil is not recommended for use more then once a day.
• If your erection continues longer than 4 hours , you should consult your health care provider.

Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Vardenafil will experience it or any other.

• an allergic reaction such as : breathing disorders; closing of the throat; swelling of the lips, tongue, or face; or hives)
• nausea, or angina
• pain in back
• chest pain or an irregular heartbeats
• swelling of the ankles or legs
• shortness of breath
• dizziness
• fainting
• painful and long erection
• flushing
• headache
• nasal congestion
• stomach disturbances
• sensitivity of the eyes to light;
• vision disorders

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with Vardenafil, please read the information provided with Vardenafil or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Vardenafil. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.
Especially pay attention to the following drugs:

• cimetidine (Tagamet, Tagamet HB);
• doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin)
• erythromycin (E-Mycin, Eryc, Ery-Tab) or clarithromycin (Biaxi
• itraconazole (Sporanox) or ketoconazole (Nizoral)
• heart rhythm medicine such as amiodarone (Cordarone, Pacerone), quinidine(Quinidex, Quinaglute), procainamide (Procan, Pronestyl), or sotalol (Betapace)
• HIV medicines such as amprenavir (Agenerase), tipranavir (Aptivus), darunavir (Prezista), efavirenz (Sustiva), nevirapine (Viramune), indinavir (Crixivan), saquinavir (Invirase, Fortovase), lopinavir/ritonavir (Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir), atazanavir (Reyataz), or nelfinavir (Viracept)
• carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin)
• rifampin (Rifadin, Rimactane).

Additional Information: DO NOT SHARE Vardenafil with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.