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"Dramatic" losses of a key biochemical substance in heart muscle tissue occur in the very earliest stages of diabetes induced in laboratory mice, scientists in Missouri are reporting ACS' Biochemistry, a weekly journal. Xianlin Han and colleagues did the |
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A leading authority and pioneer in the pharmacology of the signaling molecule nitric oxide (NO), Weill Cornell Medical College scientist Dr. Steven S. Gross has been selected by the National Heart, Lung, and Blood Institute (NHLBI) to receive a 2007 Nati |
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Prescribers and diabetes patients alike are wondering what to make of recent media reports of a New England Journal of Medicine study suggesting Avandia (rosiglitazone) increases heart attack risk by 43% in diabetes patients. Avandia, an oral agent for t |
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Resistin is a small protein secreted by the immune cells monocytes and macrophages, and has been linked to insulin resistance, atherosclerosis, and inflammation. Recently, studies in mice have shown that resistin is present in the mouse hypothalamus and |
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The molecule known as PPARgamma is required for the development of fat cells and is the target of antidiabetic drugs known as thiazolidinediones (TZDs). In a study appearing online in advance of publication in the June print issue of the Journal of Clini |
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Additional beneficial effects on 'cardiometabolic risk factors' beyond those expected from weight loss in trials of the anti-obesity drug rimonabant may not be due to the drug itself, reports an article in the June issue of Drug and Therapeutics Bulletin |
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The increasing prevalence of type 2 diabetes mellitus and its associated complications in young people mean better approaches and management of both are urgently needed, conclude authors of a Review published in The Lancet.
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A calmer and more considered approach to the safety of rosiglitazone (Avandia) - the GlaxoSmithKline treatment for type 2 diabetes - is needed to avoid unnecessary panic among patients, says an Editorial published Online and in an upcoming edition of The |
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In a fundamental discovery that someday may help cure type1 diabetes by allowing people to grow their own insulin-producing cells for a damaged or defective pancreas, medical researchers here have reported that they have engineered adult stem cells deriv |
