Its universality is associated with systemic regenerative effect on the body. The effects of Actovegin are most pronounced in hypoxic nature of tissue damage. Depletion of energy reserves leads to destruction of cellular membranes and cytolysis, the accumulation of lactic acid and tissue acidosis.

Effects of Actovegin:

• Increases anaerobic respiration of organs in a metabolic failure condition
• Active components of Actovegin also have insulin-like action. The treatment with Actovegin of patients suffering from insulin-dependent diabetes mellitus significantly slows the progression of diabetic angiopathies.
• Activates metabolic processes in the brain.
• Has a distinct therapeutic effect in patients with peripheral circulatory disorders. This effect is associated with increased vascularization and development of collateral circulation.
• Actovegin has immunomodulatory action.
• Improving the delivery of oxygen and reducing the severity of ischemic tissue damage, Actovegin indirectly contributes to the protein-synthesizing function of cells.

Rheumatologists are interested in practically all the points of application of Actovegin. As an important component of the therapy, Actovegin is used in rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis and many other severe rheumatic diseases. Actovegin also improves quality of life of patients with long-existing heart defects and chronic heart failure.