Drug name: Brand Celebrex

Active substance: Celecoxib

Pharmacological effects: The active ingredient of Celebrex is celecoxib which is an anti-inflammatory agent that selectively inhibits COX-2. The drug exerts anti-inflammatory, antipyretic and analgesic effect.

Indications: The drug is indicated in treatment of:

• Rheumatoid arthritis
• Reactive synovitis
• Osteoarthrosis
• Bechterew's disease
• Joint syndrome in gout acute stage
• Psoriatic arthritis
• Primary dysmenorrhea
• Pain syndrome of different intensity

Warnings and Precautions: The drugs should not be used in the following conditions:

• Hypersensitivity to any components of the preparations.
• Samter's triad
• Stomach and duodenal ulcer
• Ulcerous colitis
• Chronic heart failure
• Hypertension
• Liver failure
• Renal failure
• Alcoholism

The drug should be used with caution:

• Pregnancy
• Lactation period

Side effects: Drugs may cause side-effects which in specific patients may manifest differently. In the following paragraph we want to underline the most serious and frequent side effect of Celebrex that  were identified by the drug manufacturers. The possibility of the adverse effect manifestation depends only on the individual and his specific traits. Celecoxib side effects include:

• Gastrointestinal tract: Abdominal pain, nausea, vomiting heartburn, decreased appetite, diarrhea, gastrointestinal ulcer, gigival bleeding, liver dysfunction
• CNS: headache, dizziness, somnolence, insomnia, depression, agitation
• Cardiovascular system: hypertension, tachycardia
• Sensory organs: decreased hearing, ear ringing
• Respiratory system: throat pain, coughing, bronchospasm, dyspnea,

• Urogenital system: renal failure, edema syndrome
• Haemopoietic system: agranulocytosis, leukopenia, anemia, thrombocytopenia
• Allergic reactions
• Other: alopecia, increased sweating

For full information on any risks and adverse effects associated with Celebrex, please consult your doctor, read the included leaflet or contact our customer support service.

Interactions: Before using Celecoxib please tell your doctor which drugs or supplements you are already taking including those bought without a prescription. Also check if any additional medicine which you will take during the course of Celebrex therapy are safe in combination. Especially mention if you are taking the following groups of drugs:

• Uricosuric
• Anticoagulants
• Antiaggregants
• Fibrinolytics
• Glucocorticosteroids
• Hormones
• Diuretics
• Hypertension treatment
• Antimycotics
• Antacids
• Cholesterol treatment
• Antiepileptics
• Anti-metabolites

Patients information: Celebrex is not to be shared with healthy individuals. It is strictly FORBIDDEN to use the drugs in treatment of any conditions unrelated to their indications. The product as well as utilized vials, syringes, needles if used during the  course of treatment should be kept out of reach of children and never reused.