Similar Drugs

Generic Synthroid

Levoxyl

Synthroid

Pharmacological effects:

Levothyroxine is an efficient and safe remedy of replacement and suppressive therapy for most diseases of the thyroid gland. It represents a synthetic thyroid hormone; levogyratory isomer of thyroxine (T4). The drug regulates the metabolism, stimulates growth, development, metabolism of proteins, fats and carbohydrates, increases the functional activity of the cardiovascular and central nervous systems.

Indications:

• Hypothyroid states of different etiologies: primary and secondary hypothyroidism, congenital and acquired hypothyroidism; cerebrohypophyseal diseases that occur with hypothyroidism, obesity with symptoms of hypothyroidism, myxedema, cretinism, hypothyroidism after surgery or as a result of thyroiditis (including autoimmune)
• Euthyroid benign goiter, euthyroid hyperplasia of the thyroid gland, thyroid suppressive therapy of multinodular goitre (as monotherapy or in combination with potassium iodide)
• Thyrostatic treatment of hyperthyroidism after reaching the euthyroid state; diffuse toxic goiter after compensation of hyperthyroidism with thyreostatics (monotherapy or in combination therapy)
• Hashimoto's thyroiditis, Graves' disease (combination therapy)
• thyrotropin dependent highly differentiated papillary or follicular thyroid carcinomas (combination therapy)
• replacement therapy and prevention of recurrence of goiter after thyroid gland resection
• replacement therapy and prevention of recurrence after surgical treatment of thyroid malignancy (thyroidectomy for thyroid cancer)
• differential diagnostic test of thyroid suppression (as a diagnostic agent)

Warnings and Precautions: The drugs should not be used in the following conditions:

• hypersensitivity to any components of the preparations.
• untreated thyrotoxicosis
• severe coronary insufficiency, acute myocardial infarction, angina pectoris
• severe atherosclerosis
• acute myocarditis
• severe arrhythmias
• severe congestive heart failure
• severe hypertension
• uncontrolled adrenal insufficiency, untreated Addison's disease
• elderly patients (over 65)

Side effects: Drugs may cause side-effects which in specific patients may manifest differently. In the following paragraph we want to underline the most serious and frequent side effect of Levothyroxine that were identified by the drug manufacturers. The possibility of the adverse effect manifestation depends only on the individual and his specific traits. Levothroid side effects include:

• tachycardia, arrhythmia, angina (chest pain), tremors
• sleep disturbances, insomnia, weakness, anxiety
• increased sweating, hyperhidrosis, loss of body weight
• vomiting, diarrhea , hyperglycemia

For full information on any risks and adverse effects associated with Levothroid, please consult your doctor, read the included leaflet or contact our customer support service.

Interactions: Before using Levothyroxine please tell your doctor which drugs or supplements you are already taking including those bought without a prescription. Also check if any additional medicine which you will take during the course of Levothroid therapy are safe in combination. Especially mention if you are taking the following groups of drugs:

• insulin and oral antidiabetic drugs
• cardiac glycosides
• antidepressants
• oral anticoagulants (coumarin derivatives)
• anticonvulsants
• salicylates
• diuretics in high doses
• lipid-lowering drugs
• estrogens
• antimalarial drugs
• anabolic steroids
• asparaginase
• antiestrogens
• immunosuppressive drugs
• aminosalicylic acid
• antithyroid drugs
• beta-blockers

Patients information: Levothroid is not to be shared with healthy individuals. It is strictly FORBIDDEN to use the drugs in treatment of any conditions unrelated to their indications. The product as well as utilized vials, syringes, needles if used during the course of treatment should be kept out of reach of children and never reused.