Similar Drugs

Generic Synthroid

Levothroid

Levoxyl

Pharmacological effects:

Synthroid is a synthetic product of thyroid hormone, a thyroxine levogyrate isomer. After partial conversion to triiodothyronine (in the liver and kidneys) and transition to the body's cells, it influences the development and growth of tissues and on metabolism.

In small doses, levothyroxine sodium has anabolic effect on protein and fat metabolism. In moderate doses, it stimulates the growth and development, increases the oxygen demand of tissues, stimulates the metabolism of proteins, fats and carbohydrates, increases the functional activity of the cardiovascular system and central nervous system. In high doses, the drug inhibits the production of TTRG and TSH.

Indications:

• Hypothyroidism
• Euthyroid goiter
• Replacement therapy for prevention of recurrence of goiter after thyroid gland resection
• Thyroid cancer (after surgery)
• Toxic goiter: after reaching the euthyroid state by thyreostatics (as a combination or monotherapy)
• Diagnostic agent during the thyroid suppression test

Warnings and Precautions: The drugs should not be used in the following conditions:

• Uncontrolled thyrotoxicosis
• Uncontrolled pituitary insufficiency
• Uncontrolled insufficiency of adrenal cortex
• Acute heart attack
• Acute myocarditis
• Acute pancarditis
• Reactions of hypersensitivity to any of the medication ingredients
• The medication should be used with caution in: coronary heart disease (atherosclerosis, stenocardia, heart attacks in anamnesis), arterial hypertension, arrhythmia, diabetes, malabsorption syndrome.

Side effects: Drugs may cause side-effects which in specific patients may manifest differently. In the following paragraph we want to underline the most serious and frequent side effect of levothyroxine sodium that were identified by the drug manufacturers. The possibility of the adverse effect manifestation depends only on the individual and his specific traits. Synthroid side effects include:

• Skin rash
• Hives
• Itching
• Swelling of the lips, mouth and throat

High doses of Levothyroxine include:

• Increased sweating
• Hot flashes
• Menstrual problems
• High blood pressure
• Seizures
• Increased appetite
• Tachycardia
• Insomnia
• Hair loss

For full information on any risks and adverse effects associated with Synthroid, please consult your doctor, read the included leaflet or contact our customer support service.

Interactions: Before using Synthroid please tell your doctor which drugs or supplements you are already taking including those bought without a prescription. Also check if any additional medicine which you will take during the course of levothyroxine sodium therapy are safe in combination. Especially mention if you are taking the following groups of drugs:

• Antacids
• Antidepressants
• Calcium supplements
• Tuberculosis medications
• Weight loss pills
• Osteoporosis treatment in post-menopausal women
• Xantines
• Blood thinners
• Bile acid sequestrates
• Diabetes medications
• Estrogens
• Iron containing drugs and supplements

Patients information: Synthroid is not to be shared with healthy individuals. It is strictly FORBIDDEN to use the drugs in treatment of any conditions unrelated to their indications. The product as well as utilized vials, syringes, needles if used during the course of treatment should be kept out of reach of children and never reused.